Abstract
The interaction of sucrose and starch with bacterial glucosyltransferases and human salivary amylase may enhance the pathogenic potential of Streptococcus mutans within biofilms by influencing the structural organization of the extracellular matrix and modulating the expression of genes involved in exopolysaccharide synthesis and specific sugar transport and two-component systems.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Amylases / metabolism
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Biofilms / growth & development*
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Glucosyltransferases / metabolism
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Humans
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Protein Binding
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Saliva / enzymology
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Starch / metabolism*
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Streptococcus mutans / growth & development*
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Streptococcus mutans / metabolism*
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Sucrose / metabolism*
Substances
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Sucrose
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Starch
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Glucosyltransferases
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Amylases