Abstract
Panton-Valentine leukocidin (PLV) is a toxin produced by Staphylococcus aureus. Previously described as responsible for furunculoses and cutaneous abscesses, it was recently found to cause necrotizing pneumonia, generally lethal. We describe a case of necrotizing pneumonia caused by S. aureus containing PLV with an atypical form (bubble form), which had a good outcome despite several risk factors for death: hemoptysis, leukopenia, erythrodermia.
MeSH terms
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Adolescent
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Anti-Bacterial Agents / administration & dosage
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Anti-Bacterial Agents / therapeutic use
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Anti-Inflammatory Agents / administration & dosage
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Anti-Inflammatory Agents / therapeutic use
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Bacterial Toxins*
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Clindamycin / administration & dosage
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Clindamycin / therapeutic use
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Drug Therapy, Combination
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Exotoxins*
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Follow-Up Studies
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Humans
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Leukocidins*
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Male
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Methylprednisolone / administration & dosage
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Methylprednisolone / therapeutic use
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Oxacillin / administration & dosage
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Oxacillin / therapeutic use
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Pneumonia, Staphylococcal* / diagnosis
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Pneumonia, Staphylococcal* / diagnostic imaging
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Pneumonia, Staphylococcal* / drug therapy
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Pneumonia, Staphylococcal* / microbiology
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Pristinamycin / administration & dosage
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Pristinamycin / therapeutic use
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Radiography, Thoracic
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Risk Factors
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Staphylococcus aureus* / metabolism
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Time Factors
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Tomography, X-Ray Computed
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Treatment Outcome
Substances
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Anti-Bacterial Agents
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Anti-Inflammatory Agents
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Bacterial Toxins
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Exotoxins
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Leukocidins
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Panton-Valentine leukocidin
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Pristinamycin
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Clindamycin
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Oxacillin
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Methylprednisolone