Nosocomial bloodstream infections in children: an 8-year experience at a tertiary-care hospital in Finland

Clin Microbiol Infect. 2008 Nov;14(11):1072-5. doi: 10.1111/j.1469-0691.2008.02079.x.

Abstract

Laboratory-based surveillance at a Finnish paediatric tertiary-care centre during the period 1999-2006 identified 739 nosocomial bloodstream infections (BSIs) (1.6 BSIs/1000 patient-days). High rates were detected among haematology patients (4.9 BSIs/1000 patient-days) and neonatology patients (3.2 BSIs/1000 patient-days). Most BSIs (95%) were primary infections, and 75% of those were associated with a central line. The most common pathogens were coagulase-negative staphylococci (52%), Staphylococcus aureus (7%) and Candida species (6%). The overall mortality rate within 7 days after the first positive blood culture was 3%. Those who died were more likely to have been admitted to an intensive-care unit or to have undergone surgery.

MeSH terms

  • Adolescent
  • Bacterial Infections / epidemiology*
  • Bacterial Infections / microbiology
  • Blood / microbiology
  • Child
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Cross Infection / mortality
  • Finland / epidemiology
  • Humans
  • Infant, Newborn
  • Intensive Care Units
  • Mycoses / epidemiology*
  • Mycoses / microbiology
  • Prevalence
  • Risk Factors
  • Sepsis / epidemiology*
  • Sepsis / microbiology
  • Sepsis / mortality