Several lower-rim perfluoroalkylated (fluorous) calix[4]arenes have been synthesized by O-alkylation of the parent calix[4]arene. The compounds are formed in the cone conformation. They are soluble in several fluorous solvents and show promise for use in sensing, selective extractions and other applications.
Keywords: (perfluoroalkyl)alkyl aryl ethers; calixarene; fluorous; hydrofluoroethers; organofluorine.