We develop a novel method for structure determination of confined fluids using diffraction-grating-based x-ray interferometry.Within this approach, diffraction from a microfluidic array, which acts both as confinement and transmission diffraction grating, provides the reference wave, whereas the density modulations of the confined fluid, acting as a weak phase object, generate the object wave. The ensemble-averaged density profile of the fluid perpendicular to the confining channel is then unambiguously obtained from the interference between the reference and object waves by direct Fourier inversion.
(c) 2008 Optical Society of America