From MEFs to Matrigel 3: passaging hESCs from Matrigel onto Matrigel

J Vis Exp. 2008 Jun 10:(16):832. doi: 10.3791/832.

Abstract

This video demonstrates how to maintain the growth of human embryonic stem cells (hESCs) in feeder cell-free conditions and how to continuously passage hESCs in feeder cell-free conditions. Confirmation of hESC pluripotency grown in feeder cell-free conditions by immunofluorescence microscopy is also demonstrated.

Publication types

  • Research Support, Non-U.S. Gov't
  • Video-Audio Media

MeSH terms

  • Animals
  • Cell Culture Techniques / methods*
  • Collagen*
  • Drug Combinations
  • Embryo, Mammalian
  • Embryonic Stem Cells / cytology*
  • Fibroblasts / cytology*
  • Humans
  • Laminin*
  • Mice
  • Proteoglycans*

Substances

  • Drug Combinations
  • Laminin
  • Proteoglycans
  • matrigel
  • Collagen