Abstract
Our studies have focused on understanding the mechanisms of interactions between the indigenous intestinal flora and the mammalian host in both physiological and nonphysiological conditions. In particular, we have focused on the function of innate microbial pattern recognition by Toll-like receptors in the context of tissue injury and repair, spontaneous colitis, and postnatal development.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Aging / immunology
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Animals
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Humans
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Immunity, Innate / immunology*
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Inflammatory Bowel Diseases / immunology
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Inflammatory Bowel Diseases / pathology
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Interleukin-10 / immunology
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Interleukin-10 / metabolism
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Intestines / growth & development
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Intestines / immunology*
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Intestines / microbiology*
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Toll-Like Receptors / immunology
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Toll-Like Receptors / metabolism
Substances
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Toll-Like Receptors
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Interleukin-10