Radiological-pathological correlation in intratumoural tissue components of solid lung tumours

Radiol Med. 2009 Mar;114(2):173-89. doi: 10.1007/s11547-008-0354-6. Epub 2008 Dec 11.
[Article in English, Italian]

Abstract

The aim of this paper is to describe the intratumoural tissue components of solid lung tumours evidenced by macroscopic and/or microscopic examination of the autopsy or surgical specimen and visible on computed tomography (CT) without and with contrast material administration. Seven intratumoural tissue components can be identified both at CT and at pathology: (1) solid component, (2) haemorrhagic component, (3) coagulation necrosis, (4) liquefaction necrosis, (5) parenchymal consolidation, (6) diffuse peripheral component and (7) fibrotic component. Necrotic and haemorrhagic components are typically observed in malignant lesions, whereas solid and fibrotic components may be seen both in solid lung malignancies and in benign lesions.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma / diagnostic imaging
  • Adenocarcinoma / pathology
  • Cadaver
  • Carcinoma, Bronchogenic / diagnostic imaging*
  • Carcinoma, Bronchogenic / pathology*
  • Carcinoma, Non-Small-Cell Lung / diagnostic imaging
  • Carcinoma, Non-Small-Cell Lung / pathology
  • Carcinoma, Squamous Cell / diagnostic imaging
  • Carcinoma, Squamous Cell / pathology
  • Fibrosis / diagnostic imaging
  • Hemorrhage / diagnostic imaging
  • Humans
  • Lung Neoplasms / diagnostic imaging*
  • Lung Neoplasms / pathology*
  • Necrosis / diagnostic imaging
  • Radiographic Image Enhancement
  • Radiographic Image Interpretation, Computer-Assisted
  • Small Cell Lung Carcinoma / diagnostic imaging
  • Small Cell Lung Carcinoma / pathology
  • Tomography, X-Ray Computed*