Abstract
The application of air stable preformed [(R)-BINAP]PdBr2, [(S)-BINAP]PdBr2, [(R)-Tol-BINAP]PdBr2, and [(S,S)-CHIRAPHOS]PdBr2 complexes in the one-pot asymmetric reductive amination of various carbonyl compounds, leading to chiral amines in very good yields with high enantioselectivities (<99% ee), is reported.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Air
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Amination
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Aniline Compounds / chemistry
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Catalysis
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Crystallography, X-Ray
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Hydrogen / chemistry
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Ketones / chemistry*
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Oxidation-Reduction
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Palladium / chemistry*
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Stereoisomerism
Substances
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Aniline Compounds
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Ketones
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Palladium
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Hydrogen
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aniline