Abstract
The effects of water extract and ether extract of Flos Caryophylli have been investigated by four experimental gastric ulcer models, choleresis in rats, two diarrhea models in mice, two pain stimulations in mice, and acute liver injury induced by CCl4 in rats. The results suggest that the action of Flos Caryophylli on dispelling the cold by warming the middle-jiao and curing abdominalgia is related to its anti-ulcer, choleresis increasing, anti-diarrhea and analgesic functions.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Analgesics / pharmacology*
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Analgesics / therapeutic use
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Animals
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Anti-Ulcer Agents / pharmacology*
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Anti-Ulcer Agents / therapeutic use
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Bile / metabolism
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Carbon Tetrachloride
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Chemical and Drug Induced Liver Injury / drug therapy
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Diarrhea / drug therapy
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Drugs, Chinese Herbal / pharmacology*
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Drugs, Chinese Herbal / therapeutic use
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Female
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Male
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Medicine, Chinese Traditional*
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Mice
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Pain / drug therapy*
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Pain / physiopathology
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Rats
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Rats, Inbred Strains
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Sensory Thresholds / drug effects
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Stomach Ulcer / drug therapy*
Substances
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Analgesics
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Anti-Ulcer Agents
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Drugs, Chinese Herbal
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Carbon Tetrachloride