Carboplatin and paclitaxel adjuvant chemotherapy in primitive neuroectodermal tumor of the uterine corpus

Jay P Shah; Jodilyn Jelsema; Christopher S Bryant; Rouba Ali-Fehmi; John M Malone Jr

doi:10.1016/j.ajog.2008.08.056

Carboplatin and paclitaxel adjuvant chemotherapy in primitive neuroectodermal tumor of the uterine corpus

Am J Obstet Gynecol. 2009 Feb;200(2):e6-9. doi: 10.1016/j.ajog.2008.08.056. Epub 2008 Dec 25.

Authors

Jay P Shah¹, Jodilyn Jelsema, Christopher S Bryant, Rouba Ali-Fehmi, John M Malone Jr

Affiliation

¹ Division of Gynecology Oncology, Wayne State University and Karmanos Cancer Center, Detroit, MI 48201, USA. [email protected]

PMID: 19110219
DOI: 10.1016/j.ajog.2008.08.056

Abstract

Primitive neuroectodermal tumor of the uterine corpus (PNET) is rare and appears to have an aggressive clinical course. We report on a postmenopausal woman with optimal surgically cytoreduced advanced-stage PNET in which adjuvant combination chemotherapy with platinum and taxane agents was unsuccessful in extending her disease-free survival.

Publication types

Case Reports
Review

MeSH terms

Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
Carboplatin / administration & dosage
Chemotherapy, Adjuvant
Combined Modality Therapy
Female
Humans
Middle Aged
Neuroectodermal Tumors, Primitive / complications
Neuroectodermal Tumors, Primitive / drug therapy*
Neuroectodermal Tumors, Primitive / therapy
Paclitaxel / administration & dosage
Postmenopause
Radiotherapy, Adjuvant
Uterine Hemorrhage / etiology
Uterine Neoplasms / complications
Uterine Neoplasms / drug therapy*
Uterine Neoplasms / therapy

Substances

Carboplatin
Paclitaxel