Flexible miniature compound lens design for high-resolution optical coherence tomography balloon imaging catheter

J Biomed Opt. 2008 Nov-Dec;13(6):060502. doi: 10.1117/1.3037340.

Abstract

We report on a new optics design for an optical coherence tomography (OCT) balloon imaging catheter. The design involves a miniature compound gradient-index (GRIN) rod lens, which consists of a fiber optic mode-field reducer and relay rod lenses to achieve predictable high lateral resolution at a desired large working distance. The compound lens design significantly simplifies the engineering process for an OCT catheter and enables 3-D full circumferential cross sectional imaging of large luminal organs such as human esophagus. An as-designed OCT catheter is developed and demonstrated for real-time in vivo swine esophagus imaging in a 3-D spiral fashion.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Catheterization / instrumentation*
  • Computer-Aided Design
  • Equipment Design
  • Equipment Failure Analysis
  • Esophagoscopes*
  • Image Enhancement / instrumentation*
  • Lenses*
  • Miniaturization
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Tomography, Optical Coherence / instrumentation*