Abstract
Six novel alleles, three human leukocyte antigen (HLA)-B and three HLA-DRB1 alleles, are described. Five of the variants are single nucleotide substitutions from their most homologous allele, of which three result in amino acid changes (B*3572, *9509 and DRB1*1157) and two are silent substitutions (B*370103 and DRB1*150204). DRB1*0462 differs by three nucleotide substitutions that alter two amino acids.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Alleles
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Amino Acid Sequence
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Amino Acid Substitution
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HLA-B Antigens / genetics*
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HLA-DR Antigens / genetics*
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HLA-DRB1 Chains
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Humans
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Molecular Sequence Data
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Singapore
Substances
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HLA-B Antigens
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HLA-DR Antigens
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HLA-DRB1 Chains
Associated data
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GENBANK/DQ244125
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GENBANK/DQ244126
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GENBANK/DQ436824
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GENBANK/DQ436825
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GENBANK/DQ535034
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GENBANK/EF078990
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GENBANK/EF173483
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GENBANK/EU146146