Magnetic resonance imaging findings of tamoxifen-associated uterine Müllerian adenosarcoma: a case report

Acta Radiol. 2008 Sep;49(7):848-51.

Abstract

Müllerian adenosarcoma of the uterus is a rare biphasic tumor, which was first described in 1974. Recent studies have suggested an association with tamoxifen therapy, but there have been few reports with detailed imaging findings. We present a case with magnetic resonance imaging (MRI) findings of this rare tumor in a woman who received long-term tamoxifen therapy for breast cancer. In addition, myometrial invasion was detected more accurately with MRI compared to ultrasound in this one single case.

Publication types

  • Case Reports

MeSH terms

  • Adenosarcoma / chemically induced*
  • Adenosarcoma / diagnosis*
  • Adenosarcoma / pathology
  • Adenosarcoma / surgery
  • Antineoplastic Agents, Hormonal / adverse effects*
  • Antineoplastic Agents, Hormonal / therapeutic use
  • Breast Neoplasms / drug therapy
  • Female
  • Humans
  • Hysterectomy
  • Magnetic Resonance Imaging / methods*
  • Middle Aged
  • Mullerian Ducts / pathology*
  • Neoplasm Invasiveness
  • Tamoxifen / adverse effects*
  • Tamoxifen / therapeutic use
  • Uterine Neoplasms / chemically induced*
  • Uterine Neoplasms / diagnosis*
  • Uterine Neoplasms / pathology
  • Uterine Neoplasms / surgery

Substances

  • Antineoplastic Agents, Hormonal
  • Tamoxifen