Rapid detection of Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) in wound specimens and blood cultures: multicenter preclinical evaluation of the Cepheid Xpert MRSA/SA skin and soft tissue and blood culture assays

J Clin Microbiol. 2009 Mar;47(3):823-6. doi: 10.1128/JCM.01884-08. Epub 2009 Jan 14.

Abstract

A multicenter preclinical evaluation was conducted to evaluate the performance of two Cepheid Xpert assays for detection of methicillin-resistant Staphylococcus aureus (MRSA) and S. aureus. Sensitivity was 97.1% and 98.3% for MRSA in wound and blood culture specimens, respectively. Sensitivity was 100% for S. aureus from both specimen types.

Publication types

  • Evaluation Study
  • Multicenter Study

MeSH terms

  • Bacteriological Techniques / methods*
  • Blood / microbiology*
  • Humans
  • Sensitivity and Specificity
  • Staphylococcal Infections / diagnosis*
  • Staphylococcus aureus / isolation & purification*
  • Wounds and Injuries / microbiology*