Effect of the microbial constituents, LPS and BCG, on the glycosaminoglycans of chondrocyte cultures

P D Kittlick; D Engelmann

doi:10.1016/s0232-1513(11)80014-9

Effect of the microbial constituents, LPS and BCG, on the glycosaminoglycans of chondrocyte cultures

Exp Pathol. 1991;42(3):145-50. doi: 10.1016/s0232-1513(11)80014-9.

Authors

P D Kittlick¹, D Engelmann

Affiliation

¹ Friedrich Schiller University Jena, Institute of Pathology, F.R.G.

PMID: 1915758
DOI: 10.1016/s0232-1513(11)80014-9

Abstract

Earlier we reported that articular chondrocytes in monolayer culture produce pericellular proteoglycans both with short and long half lives, T-1 and T-2 (Kittlick et al. 1991 b). Now monolayer cultures have been investigated to assess the influence on the metabolism of pericellular proteoglycans or glycosaminoglycans by lipopolysaccharide of E. coli and S. typhimurium as well as by Bacillus Calmette-Guérin.

MeSH terms

Animals
Cartilage, Articular / cytology*
Cartilage, Articular / drug effects
Cartilage, Articular / metabolism
Cells, Cultured
Escherichia coli / metabolism
Glycosaminoglycans / metabolism*
Lipopolysaccharides / metabolism
Lipopolysaccharides / physiology*
Mycobacterium bovis / physiology*
Proteoglycans / metabolism
Rabbits
Sulfur / metabolism
Sulfur Radioisotopes

Substances

Glycosaminoglycans
Lipopolysaccharides
Proteoglycans
Sulfur Radioisotopes
Sulfur