Broadband slab selection with B1+ mitigation at 7T via parallel spectral-spatial excitation

Magn Reson Med. 2009 Feb;61(2):493-500. doi: 10.1002/mrm.21834.

Abstract

Chemical shift imaging benefits from signal-to-noise ratio (SNR) and chemical shift dispersion increases at stronger main field such as 7 Tesla, but the associated shorter radiofrequency (RF) wavelengths encountered require B1+ mitigation over both the spatial field of view (FOV) and a specified spectral bandwidth. The bandwidth constraint presents a challenge for previously proposed spatially tailored B1+ mitigation methods, which are based on a type of echovolumnar trajectory referred to as "spokes" or "fast-kz". Although such pulses, in conjunction with parallel excitation methodology, can efficiently mitigate large B1+ inhomogeneities and achieve relatively short pulse durations with slice-selective excitations, they exhibit a narrow-band off-resonance response and may not be suitable for applications that require B1+ mitigation over a large spectral bandwidth. This work outlines a design method for a general parallel spectral-spatial excitation that achieves a target-error minimization simultaneously over a bandwidth of frequencies and a specified spatial-domain. The technique is demonstrated for slab-selective excitation with in-plane B1+ mitigation over a 600-Hz bandwidth. The pulse design method is validated in a water phantom at 7T using an eight-channel transmit array system. The results show significant increases in the pulse's spectral bandwidth, with no additional pulse duration penalty and only a minor tradeoff in spatial B1+ mitigation compared to the standard spoke-based parallel RF design.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / methods*
  • Magnetic Resonance Imaging / methods*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Whole Body Imaging / methods*