Abstract
An outbreak of viral encephalitis occurred in northern India in 2006. Attempts to identify an etiologic agent in cerebrospinal fluid by using reverse transcription-PCR showed positivity to enterovirus (EV) in 66 (21.6%) of 306 patients. Sequencing and phylogenetic analyses of PCR products from 59 (89.3%) of 66 specimens showed similarity with EV-89 and EV-76 sequences.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acute Disease
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Adolescent
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Animals
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Cell Line
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Cell Line, Tumor
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Cerebrospinal Fluid / virology*
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Child
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Child, Preschool
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Cricetinae
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Disease Outbreaks*
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Encephalitis, Viral* / diagnosis
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Encephalitis, Viral* / epidemiology
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Encephalitis, Viral* / virology
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Enterovirus Infections / diagnosis
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Enterovirus Infections / epidemiology
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Enterovirus Infections / virology
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Enterovirus* / classification
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Enterovirus* / genetics
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Enterovirus* / isolation & purification
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Humans
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India / epidemiology
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Infant
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Infant, Newborn
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Phylogeny
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RNA, Viral / analysis
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RNA, Viral / isolation & purification
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Reverse Transcriptase Polymerase Chain Reaction
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Sequence Analysis, DNA