Signal transducer and activator of transcription 5 tyrosine phosphorylation for the diagnosis and monitoring of patients with severe combined immunodeficiency

J Allergy Clin Immunol. 2009 Feb;123(2):505-8. doi: 10.1016/j.jaci.2008.11.041.
No abstract available

Publication types

  • Letter

MeSH terms

  • B-Lymphocytes / immunology
  • B-Lymphocytes / metabolism
  • Biomarkers / metabolism
  • Electrophoretic Mobility Shift Assay
  • Female
  • Humans
  • Interleukin-2 / pharmacology
  • Killer Cells, Natural / immunology
  • Killer Cells, Natural / metabolism
  • Male
  • Phosphorylation
  • Phosphotyrosine / metabolism*
  • STAT5 Transcription Factor / drug effects
  • STAT5 Transcription Factor / genetics
  • STAT5 Transcription Factor / metabolism*
  • Severe Combined Immunodeficiency / diagnosis*
  • Severe Combined Immunodeficiency / genetics
  • Signal Transduction
  • T-Lymphocytes / immunology
  • T-Lymphocytes / metabolism
  • Tyrosine / metabolism

Substances

  • Biomarkers
  • IL2 protein, human
  • Interleukin-2
  • STAT5 Transcription Factor
  • Phosphotyrosine
  • Tyrosine