Effect of sitagliptin on the pharmacokinetics of simvastatin

J Clin Pharmacol. 2009 Apr;49(4):483-8. doi: 10.1177/0091270008330983. Epub 2009 Feb 9.
No abstract available

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cross-Over Studies
  • Dipeptidyl-Peptidase IV Inhibitors / administration & dosage*
  • Drug Interactions
  • Female
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / pharmacokinetics*
  • Hypolipidemic Agents / administration & dosage*
  • Hypolipidemic Agents / pharmacokinetics*
  • Male
  • Pyrazines / administration & dosage
  • Pyrazines / pharmacology*
  • Simvastatin / administration & dosage
  • Simvastatin / pharmacokinetics*
  • Sitagliptin Phosphate
  • Time Factors
  • Triazoles / administration & dosage
  • Triazoles / pharmacology*

Substances

  • Dipeptidyl-Peptidase IV Inhibitors
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Hypolipidemic Agents
  • Pyrazines
  • Triazoles
  • Simvastatin
  • Sitagliptin Phosphate