Chromosome dynamics: the case of the missing condensin

Curr Biol. 2009 Feb 10;19(3):R127-9. doi: 10.1016/j.cub.2008.12.004.

Abstract

Condensins are conserved protein complexes that play integral roles in chromosome dynamics during mitosis and meiosis. Caenorhabditis elegans has been thought to be unusual in that it appeared to lack a typical condensin I complex. However, recent biochemical excavating in the nematode has unearthed the 'missing' condensin I complex as well as the worm homologs of long-lost canonical condensin subunits.

Publication types

  • Review

MeSH terms

  • Adenosine Triphosphatases / genetics
  • Adenosine Triphosphatases / metabolism*
  • Animals
  • Caenorhabditis elegans / genetics
  • Caenorhabditis elegans / physiology*
  • Cell Nucleus Division / physiology*
  • Chromosomes / physiology*
  • DNA-Binding Proteins / genetics
  • DNA-Binding Proteins / metabolism*
  • Models, Molecular
  • Multiprotein Complexes / genetics
  • Multiprotein Complexes / metabolism*

Substances

  • DNA-Binding Proteins
  • Multiprotein Complexes
  • condensin complexes
  • Adenosine Triphosphatases