Identification of cyclophilin as a novel allergen from Platanus orientalis pollens by mass spectrometry

Nazanin Pazouki; Mojtaba Sankian; Priscilla T Y Leung; Taher Nejadsattari; Ramezan-Ali Khavari-Nejad; Abdol-Reza Varasteh

doi:10.1016/j.jbiosc.2008.10.016

Identification of cyclophilin as a novel allergen from Platanus orientalis pollens by mass spectrometry

J Biosci Bioeng. 2009 Feb;107(2):215-7. doi: 10.1016/j.jbiosc.2008.10.016.

Authors

Nazanin Pazouki¹, Mojtaba Sankian, Priscilla T Y Leung, Taher Nejadsattari, Ramezan-Ali Khavari-Nejad, Abdol-Reza Varasteh

Affiliation

¹ Biology Department, Science and Research Branch, Islamic Azad University (IAU), Tehran, Iran.

PMID: 19217563
DOI: 10.1016/j.jbiosc.2008.10.016

Abstract

Oriental plane trees are an important source of airborne allergens in cities of southwest Asia. In spite of extensive studies on Platanus acerifolia allergy, there are no reports on the molecular characterization of pollen allergens from Platanus orientalis trees. In this study, a newly recognized member of cyclophilin family with a molecular weight of 18 kDa was identified as being partly responsible for IgE reactivity of P. orientalis pollen extract.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Allergens / chemistry*
Amino Acid Sequence
Cyclophilins / chemistry*
Electrophoresis, Polyacrylamide Gel
Molecular Sequence Data
Molecular Weight
Plants / chemistry*
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Substances

Allergens
Cyclophilins