Abstract
A new naphthalene derivative, 1-methyl-2,3-methylenedioxy-6-naphthalenecarboxylic acid methyl ester (1), and a new alkaloid, ( +/- )-1-phenyl-2-imido-1-propanol (2), together with the four known compounds, ephedrine, pseudoephedrine, N-methylephedrine, and 6-methoxykynurenic acid, have been isolated from the stems of Ephedra sinica, a famous traditional Chinese herbal medicine. The structures of 1 and 2 were determined by spectroscopic methods, including 1D- and 2D-NMR experiments as well as HR-EI-MS analysis.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkaloids / chemistry
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Alkaloids / isolation & purification*
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Ephedra sinica / chemistry*
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Ephedrine / analogs & derivatives
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Ephedrine / isolation & purification
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Molecular Structure
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Naphthalenes / chemistry
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Naphthalenes / isolation & purification*
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Nuclear Magnetic Resonance, Biomolecular
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Plant Stems / chemistry
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Pseudoephedrine / isolation & purification
Substances
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1-methyl-2,3-methylenedioxy-6-naphthalenecarboxylic acid methyl ester
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Alkaloids
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Drugs, Chinese Herbal
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Naphthalenes
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N-methylephedrine
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Pseudoephedrine
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Ephedrine