SOCS3 inhibits TPO-stimulated, but not spontaneous, megakaryocytic growth in primary myelofibrosis

Leukemia. 2009 Jun;23(6):1186-90. doi: 10.1038/leu.2009.22. Epub 2009 Feb 19.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Proliferation
  • DNA Methylation
  • Humans
  • Megakaryocytes / pathology*
  • Primary Myelofibrosis / pathology*
  • Promoter Regions, Genetic
  • Suppressor of Cytokine Signaling 3 Protein
  • Suppressor of Cytokine Signaling Proteins / genetics
  • Suppressor of Cytokine Signaling Proteins / physiology*
  • Thrombopoietin / physiology*

Substances

  • SOCS3 protein, human
  • Suppressor of Cytokine Signaling 3 Protein
  • Suppressor of Cytokine Signaling Proteins
  • Thrombopoietin