Copper-TBAF catalyzed arylation of amines and amides with aryl trimethoxysilane

Org Biomol Chem. 2009 Mar 7;7(5):869-73. doi: 10.1039/b819510b. Epub 2009 Jan 20.

Abstract

A copper-catalyzed C-N bond forming reaction among aryl siloxane and primary, secondary amines as well as amides has been described. The reaction was conducted in the presence of P(C6F5)3 and 4 A molecular sieves in CH2Cl2 at room temperature under O2. A catalytic amount of TBAF was employed to activate aryl siloxanes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amides / chemistry*
  • Amines / chemistry*
  • Catalysis
  • Copper
  • Hydrocarbons, Aromatic / chemistry*
  • Silanes

Substances

  • Amides
  • Amines
  • Hydrocarbons, Aromatic
  • Silanes
  • Copper
  • trimethoxysilane