Abstract
For intensively pretreated pediatric patients with human immunodeficiency virus type 1 (HIV-1) infection, the treatment options available are limited. We report the case of a highly treatment-experienced 12-year-old boy with multidrug-resistant HIV-1, who was successfully treated with highly active antiretroviral therapy (HAART) including ritonavir-boosted tipranavir oral solution, a novel non-peptic protease inhibitor, and enfuvirtide.
MeSH terms
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Anti-HIV Agents / therapeutic use*
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Antiretroviral Therapy, Highly Active / methods*
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Child
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Drug Resistance, Multiple, Viral / drug effects*
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Drug Therapy, Combination
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Enfuvirtide
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HIV Envelope Protein gp41 / therapeutic use
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HIV Infections / drug therapy*
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HIV Infections / virology
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HIV-1 / drug effects*
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Humans
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Male
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Peptide Fragments / therapeutic use
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Pyridines / therapeutic use
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Pyrones / therapeutic use
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Remission Induction
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Ritonavir / therapeutic use
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Sulfonamides
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Treatment Outcome
Substances
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Anti-HIV Agents
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HIV Envelope Protein gp41
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Peptide Fragments
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Pyridines
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Pyrones
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Sulfonamides
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Enfuvirtide
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Ritonavir
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tipranavir