A 12-year-old boy with multidrug-resistant human immunodeficiency virus type 1 successfully treated with HAART including ritonavir-boosted tipranavir oral solution and enfuvirtide

Eur J Med Res. 2009 Jan 28;14(1):44-6.

Abstract

For intensively pretreated pediatric patients with human immunodeficiency virus type 1 (HIV-1) infection, the treatment options available are limited. We report the case of a highly treatment-experienced 12-year-old boy with multidrug-resistant HIV-1, who was successfully treated with highly active antiretroviral therapy (HAART) including ritonavir-boosted tipranavir oral solution, a novel non-peptic protease inhibitor, and enfuvirtide.

Publication types

  • Case Reports

MeSH terms

  • Anti-HIV Agents / therapeutic use*
  • Antiretroviral Therapy, Highly Active / methods*
  • Child
  • Drug Resistance, Multiple, Viral / drug effects*
  • Drug Therapy, Combination
  • Enfuvirtide
  • HIV Envelope Protein gp41 / therapeutic use
  • HIV Infections / drug therapy*
  • HIV Infections / virology
  • HIV-1 / drug effects*
  • Humans
  • Male
  • Peptide Fragments / therapeutic use
  • Pyridines / therapeutic use
  • Pyrones / therapeutic use
  • Remission Induction
  • Ritonavir / therapeutic use
  • Sulfonamides
  • Treatment Outcome

Substances

  • Anti-HIV Agents
  • HIV Envelope Protein gp41
  • Peptide Fragments
  • Pyridines
  • Pyrones
  • Sulfonamides
  • Enfuvirtide
  • Ritonavir
  • tipranavir