Novel HLA-DR2 and -DR3 haplotypes among Norwegian Caucasians

K S Ronningen; A Spurkland; T Iwe; L M Sollid; F Vartdal; E Thorsby

doi:10.1111/j.1399-0039.1991.tb01866.x

Novel HLA-DR2 and -DR3 haplotypes among Norwegian Caucasians

Tissue Antigens. 1991 Apr;37(4):165-7. doi: 10.1111/j.1399-0039.1991.tb01866.x.

Authors

K S Ronningen¹, A Spurkland, T Iwe, L M Sollid, F Vartdal, E Thorsby

Affiliation

¹ Institute of Transplantation Immunology, National Hospital, Oslo, Norway.

PMID: 1926125
DOI: 10.1111/j.1399-0039.1991.tb01866.x

Abstract

In the Northern European population, all DR2 haplotypes encoded by DRB1*1501 have previously been found to carry the DQA1*0102 and DQB1*0602 alleles, and DR3 haplotypes have been found to carry the DQA1*0501 and DQB1*0201 alleles. Here we report a novel recombinant DR2 haplotype carrying the DRB1*1501, DQA1*0102 and DQB1*0603 alleles as well as a novel recombinant DR3 haplotype carrying the DRB1*0301, DRB3*0101, DQA1*0102 and DQB1*0602 alleles.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Base Sequence
Female
Gene Frequency
Genes, MHC Class II
HLA-DR2 Antigen / genetics*
HLA-DR3 Antigen / genetics*
Haplotypes
Humans
Male
Molecular Sequence Data
Norway
Pedigree
Recombination, Genetic
White People / genetics*

Substances

HLA-DR2 Antigen
HLA-DR3 Antigen