The role of paroxetine in fatigue and depression of patients under chemotherapeutic treatment

Am J Ther. 2013 May-Jun;20(3):254-6. doi: 10.1097/MJT.0b013e318187de2c.

Abstract

We evaluated paroxetine for the treatment of fatigue and depression in patients with solid tumors after chemotherapy, and we found that paroxetine is effective for the treatment of depression during chemotherapy but has no benefit for the treatment of fatigue.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Antidepressive Agents, Second-Generation / therapeutic use*
  • Antineoplastic Agents / adverse effects*
  • Depression / chemically induced
  • Depression / complications
  • Depression / diagnosis
  • Depression / drug therapy*
  • Double-Blind Method
  • Drug Administration Schedule
  • Fatigue / chemically induced
  • Fatigue / complications
  • Fatigue / diagnosis
  • Fatigue / drug therapy*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Paroxetine / therapeutic use*
  • Prospective Studies
  • Surveys and Questionnaires
  • Treatment Outcome

Substances

  • Antidepressive Agents, Second-Generation
  • Antineoplastic Agents
  • Paroxetine