Initial experience with a new laparoscopic ultrasound probe for guided biopsy in the staging of upper gastrointestinal cancer

Surg Endosc. 2009 Jul;23(7):1552-8. doi: 10.1007/s00464-009-0336-3. Epub 2009 Mar 5.

Abstract

Background: Until recently, laparoscopic ultrasound (LUS)-guided biopsy has been difficult with the available probes on the market. This study aimed to present a new laparoscopic ultrasound probe (Hitachi, EUP-OL531) for guided biopsy and describe its impact on the clinical outcome for patients with upper gastrointestinal (UGI) cancer.

Methods: Patients referred with confirmed UGI cancer from June 2003 to December 2006 were included in the study. After a standard workup including computed tomography, endoscopic ultrasound, and ultrasound of the neck, operable patients underwent LUS with or without fine-needle aspiration (FNA).

Results: From a total of 175 patients, 19 (11%) underwent LUS-guided FNA after a significant lesion was found. The LUS-guided FNA confirmed distant metastasis in 14 of the 19 patients and changed the clinical management for these 14 patients (8%). There were no adverse events due to LUS or LUS-guided FNA.

Conclusion: The current results with the new LUS probe for guided FNA are encouraging in terms of its diagnostic ability, safety, and ease of use.

Publication types

  • Clinical Trial

MeSH terms

  • Aged
  • Antineoplastic Agents / therapeutic use
  • Biopsy, Fine-Needle / methods*
  • Carcinoma / complications
  • Carcinoma / diagnostic imaging
  • Carcinoma / pathology
  • Carcinoma / secondary*
  • Carcinoma / surgery
  • Carcinoma / therapy
  • Combined Modality Therapy
  • Equipment Design
  • Esophageal Neoplasms / complications
  • Esophageal Neoplasms / diagnostic imaging*
  • Esophageal Neoplasms / pathology
  • Esophageal Neoplasms / surgery
  • Esophageal Neoplasms / therapy
  • Esophageal Stenosis / diagnostic imaging
  • Esophageal Stenosis / etiology
  • Esophagogastric Junction / diagnostic imaging
  • Esophagogastric Junction / pathology
  • Esophagogastric Junction / surgery
  • Female
  • Humans
  • Laparoscopy / methods*
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / pathology
  • Liver Neoplasms / secondary
  • Lymphatic Metastasis / diagnostic imaging
  • Lymphatic Metastasis / pathology
  • Male
  • Middle Aged
  • Needles
  • Neoplasm Invasiveness / diagnostic imaging
  • Neoplasm Staging / methods*
  • Palliative Care
  • Pilot Projects
  • Prospective Studies
  • Stents
  • Stomach Neoplasms / diagnostic imaging*
  • Stomach Neoplasms / pathology
  • Stomach Neoplasms / surgery
  • Stomach Neoplasms / therapy
  • Ultrasonography, Interventional / instrumentation*
  • Ultrasonography, Interventional / methods

Substances

  • Antineoplastic Agents