Churg-Strauss syndrome in a child with IgA nephropathy

Clin Nephrol. 2009 Mar;71(3):306-9. doi: 10.5414/cnp71306.

Abstract

Churg-Strauss syndrome (CSS) is a rare systemic vasculitis associated with asthma and eosinophilia. Withdrawal of corticosteroids in asthmatic patients is known to be a powerful trigger for the development of CSS. Renal involvement in patients with CSS is commonly manifested as antineutrophil cytoplasm antibody-associated necrotizing crescentic glomerulonephritis, however, concomitant CSS and the nephrotic syndrome or IgA nephropathy are rare. We report a 12-year-old boy with CSS associated with IgA nephropathy that developed while tapering oral steroids. The patient had a history of the nephrotic syndrome and asthma.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / administration & dosage*
  • Antipruritics / administration & dosage
  • Child
  • Churg-Strauss Syndrome / complications*
  • Churg-Strauss Syndrome / drug therapy*
  • Cyclosporine / administration & dosage
  • Drug Therapy, Combination
  • Glomerulonephritis, IGA / drug therapy
  • Glomerulonephritis, IGA / etiology*
  • Humans
  • Immunosuppressive Agents / administration & dosage
  • Ketotifen / administration & dosage
  • Male
  • Pregnenediones / administration & dosage

Substances

  • Adrenal Cortex Hormones
  • Antipruritics
  • Immunosuppressive Agents
  • Pregnenediones
  • Cyclosporine
  • deflazacort
  • Ketotifen