15-Lipoxygenase inhibitory effects of prenylated flavonoids from Erythrina senegalensis

Planta Med. 2009 Aug;75(10):1168-70. doi: 10.1055/s-0029-1185449. Epub 2009 Mar 13.

Abstract

One new pterocarpan (named erybraedin F) along with seven known prenylated flavonoids were isolated from the stem and root bark of the medicinal plant Erythrina senegalensis. The structures were elucidated by 1D and 2D NMR and MS. The pterocarpans were found to be strong inhibitors of 15-lipoxygenase.

Publication types

  • Letter

MeSH terms

  • Erythrina / chemistry*
  • Flavonoids / chemistry
  • Flavonoids / pharmacology*
  • Lipoxygenase Inhibitors* / pharmacology*
  • Magnetic Resonance Spectroscopy

Substances

  • Flavonoids
  • Lipoxygenase Inhibitors