Electrochemical detection of hepatitis C virus based on site-specific DNA cleavage of BamHI endonuclease

Chem Commun (Camb). 2009 Apr 7:(13):1635-7. doi: 10.1039/b900690g. Epub 2009 Mar 2.

Abstract

We have developed a new electrochemical approach for qualitative and quantitative detection of hepatitis C virus (HCV) based on the site-specific DNA cleavage of BamHI endonuclease.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • DNA Probes
  • DNA, Viral / analysis*
  • Deoxyribonuclease BamHI / metabolism*
  • Electrochemistry / methods*
  • Hepacivirus / genetics
  • Hepacivirus / isolation & purification*

Substances

  • DNA Probes
  • DNA, Viral
  • Deoxyribonuclease BamHI