In vitro activity of micafungin against planktonic and sessile Candida albicans isolates

Melissa J Jacobson; Kathryn E Steckelberg; Kerryl E Piper; James M Steckelberg; Robin Patel

doi:10.1128/AAC.01724-08

In vitro activity of micafungin against planktonic and sessile Candida albicans isolates

Antimicrob Agents Chemother. 2009 Jun;53(6):2638-9. doi: 10.1128/AAC.01724-08. Epub 2009 Mar 23.

Authors

Melissa J Jacobson¹, Kathryn E Steckelberg, Kerryl E Piper, James M Steckelberg, Robin Patel

Affiliation

¹ Division of Infectious Diseases, Department of Medicine, Mayo Clinic College of Medicine, 200 First Street S. W., Rochester, MN 55905, USA.

Abstract

Planktonic and sessile susceptibilities to micafungin were determined for 30 clinical isolates of Candida albicans obtained from blood or other sterile sites. Planktonic and sessile MIC(90)s for micafungin were 0.125 and 1.0 microg/ml, respectively.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antifungal Agents / pharmacology*
Biofilms / drug effects
Candida albicans / drug effects*
Echinocandins / pharmacology*
Humans
Lipopeptides / pharmacology*
Micafungin
Microbial Sensitivity Tests
Plankton / microbiology*

Substances

Antifungal Agents
Echinocandins
Lipopeptides
Micafungin