Analysis of the outer retina reconstructed by high-resolution, three-dimensional spectral domain optical coherence tomography

Ophthalmic Surg Lasers Imaging. 2009 Mar-Apr;40(2):102-8. doi: 10.3928/15428877-20090301-10.

Abstract

Background and objective: A retrospective cross-sectional study was conducted to demonstrate an analysis of an outer retinal layer reconstructed by the three-dimensional and high-speed spectral domain optical coherence tomography (SD-OCT) instrument.

Patients and methods: New measurement protocols for SD-OCT and methods of analysis and visualization of the individual segmented retinal layer reconstructed by SD-OCT were proposed. Three contour maps representing mutual distances between the basal part of the retinal pigment epithelium, the junction between the inner and outer segments of photoreceptors, and a reference contour representing the shape of a healthy retina were introduced.

Results: The analysis of the outer retina was performed on pathological eyes. Three cases of central serous chorioretinopathy, age-related macular degeneration, and acute zonal occult outer retinopathy are demonstrated.

Conclusion: Three contour maps reconstructed for clinical cases demonstrate high variability of observed patterns depending on analyzed pathology. The authors believe this can help to present OCT data simultaneously in a more comprehensive and convenient way to assist in everyday clinical diagnosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Fluorescein Angiography
  • Fourier Analysis
  • Humans
  • Imaging, Three-Dimensional*
  • Middle Aged
  • Retina / anatomy & histology
  • Retinal Diseases / diagnosis*
  • Retinal Photoreceptor Cell Inner Segment / pathology*
  • Retinal Photoreceptor Cell Outer Segment / pathology*
  • Retinal Pigment Epithelium / anatomy & histology
  • Retinal Pigment Epithelium / pathology*
  • Retrospective Studies
  • Tomography, Optical Coherence*
  • Young Adult