A twelve-year experience with adrenal cortical carcinoma in a single institution: long-term survival after surgical treatment and transcatheter arterial embolization

Urol Int. 2009;82(2):222-6. doi: 10.1159/000200804. Epub 2009 Mar 19.

Abstract

Introduction: We retrospectively analyzed 6 cases of adrenal cortical carcinoma (ACC) treated during a 12-year period at a single institution.

Patients and methods: We reviewed the clinical and pathological records and updated the follow-up of the patients treated and observed in our institution between 1995 and 2006.

Results: All 6 patients underwent surgery for ACC. The mean age at diagnosis was 53.3 years (range 36-72). The median follow-up was 50.7 months (range 13-132). Three patients were clinically classified as stage II, 2 as stage III and 1 as stage IV with bone metastasis. The 5-year overall survival was 62.5%. Recurrences or metastases occurred in 4 patients. Two patients without reoperation for metastases died, and others with radical treatments such as surgery, chemotherapy, transcatheter arterial embolization and/or radiation remain alive.

Conclusions: In our experience, transcatheter arterial embolization was effective against liver metastasis.

MeSH terms

  • Adrenal Cortex Neoplasms / mortality
  • Adrenal Cortex Neoplasms / pathology
  • Adrenal Cortex Neoplasms / surgery
  • Adrenal Cortex Neoplasms / therapy*
  • Adrenalectomy*
  • Adrenocortical Carcinoma / mortality
  • Adrenocortical Carcinoma / secondary
  • Adrenocortical Carcinoma / surgery
  • Adrenocortical Carcinoma / therapy*
  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bone Neoplasms / secondary
  • Bone Neoplasms / therapy
  • Chemoembolization, Therapeutic*
  • Female
  • Humans
  • Japan
  • Liver Neoplasms / secondary
  • Liver Neoplasms / therapy
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Reoperation
  • Retrospective Studies
  • Survival Analysis
  • Time Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome