Abstract
In this Communication, the access to three different peptide loops attached to a small triazacyclophane (TAC) scaffold molecule for the mimicry of discontinuous epitopes present in, for example, antibodies is described for the first time.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Amino Acid Sequence
-
Antibodies
-
Aza Compounds / chemistry*
-
Biomimetics*
-
Epitopes / chemistry*
-
Heterocyclic Compounds, 2-Ring / chemistry*
-
Mass Spectrometry
-
Models, Molecular
-
Peptides, Cyclic / chemistry
-
Protein Conformation
-
Proteins / chemical synthesis*
-
Proteins / chemistry
Substances
-
Antibodies
-
Aza Compounds
-
Epitopes
-
Heterocyclic Compounds, 2-Ring
-
Peptides, Cyclic
-
Proteins
-
triazacyclophane