Factors affecting postoperative cerebrospinal fluid leaks after retrosigmoidal craniotomy for vestibular schwannomas

J Neurosurg. 2009 Oct;111(4):874-83. doi: 10.3171/2009.2.JNS081380.

Abstract

Object: The aim of this study was to identify patients likely to develop CSF leaks after vestibular schwannoma surgery using a retrospective analysis for the identification of risk factors.

Methods: Between January 2001 and December 2006, 420 patients underwent retrosigmoidal microsurgical tumor removal in a standardized procedure. Of these 420 patients, 363 underwent treatment for the first time, and 27 suffered from recurrent tumors. Twenty-six patients had bilateral tumors due to neurofibromatosis Type 2, and 4 patients had previously undergone radiosurgical treatment. An analysis was performed to examine the incidence of postoperative CSF fistulas in all 4 groups.

Results: The incidence of CSF leakage was higher in the tumor recurrence group (11.1%) than in patients undergoing surgery for the first time (4.4%). There were no CSF fistulas in the neurofibromatosis Type 2 group or in patients with preoperative radiosurgical treatment. Tumor size was identified as a possible risk factor in a previous study.

Conclusions: Surgery for recurrent tumors is a significant risk factor for the development of CSF leaks.

Publication types

  • Review

MeSH terms

  • Craniotomy / adverse effects*
  • Craniotomy / methods*
  • Female
  • Humans
  • Male
  • Neuroma, Acoustic / surgery*
  • Radiosurgery
  • Recurrence
  • Reoperation
  • Retrospective Studies
  • Risk Factors
  • Subdural Effusion / epidemiology
  • Subdural Effusion / etiology*
  • Treatment Outcome