Getting to the gate: crystallization of a Sac3(CID):Sus1:Cdc31 complex

Gwendolyn M Wilmes; Christine Guthrie

doi:10.1016/j.molcel.2009.03.003

Getting to the gate: crystallization of a Sac3(CID):Sus1:Cdc31 complex

Mol Cell. 2009 Mar 27;33(6):671-2. doi: 10.1016/j.molcel.2009.03.003.

Authors

Gwendolyn M Wilmes¹, Christine Guthrie

Affiliation

¹ Department of Biochemistry and Biophysics, University of California, San Francisco, 600 16th Street, Genentech Hall, San Francisco, CA 94143-2200, USA.

PMID: 19328059
DOI: 10.1016/j.molcel.2009.03.003

Abstract

In this issue of Molecular Cell, Jani et al. (2009) present the crystal structure of a region of TREX2, thereby providing a physical framework for how the transcription and export machineries might cooperate to "gate" genes to the nuclear pore.

Publication types

Comment

MeSH terms

Calcium-Binding Proteins / chemistry*
Calcium-Binding Proteins / genetics
Calcium-Binding Proteins / metabolism
Cell Cycle Proteins / chemistry*
Cell Cycle Proteins / genetics
Cell Cycle Proteins / metabolism
Crystallography, X-Ray
Nuclear Pore / genetics
Nuclear Pore / metabolism*
Nuclear Proteins / chemistry*
Nuclear Proteins / genetics
Nuclear Proteins / metabolism
Nucleocytoplasmic Transport Proteins
Porins
RNA Transport*
RNA, Messenger / metabolism*
RNA-Binding Proteins / chemistry*
RNA-Binding Proteins / genetics
RNA-Binding Proteins / metabolism
Saccharomyces cerevisiae / physiology*
Saccharomyces cerevisiae Proteins / chemistry*
Saccharomyces cerevisiae Proteins / genetics
Saccharomyces cerevisiae Proteins / metabolism

Substances

CDC31 protein, S cerevisiae
Calcium-Binding Proteins
Cell Cycle Proteins
Nuclear Proteins
Nucleocytoplasmic Transport Proteins
Porins
RNA, Messenger
RNA-Binding Proteins
SAC3 protein, S cerevisiae
Saccharomyces cerevisiae Proteins
Sus1 protein, S cerevisiae