High rate of reduced susceptibility to ciprofloxacin and ceftriaxone among nontyphoid Salmonella clinical isolates in Asia

Antimicrob Agents Chemother. 2009 Jun;53(6):2696-9. doi: 10.1128/AAC.01297-08. Epub 2009 Mar 30.

Abstract

This multinational study from Asia revealed that reduced susceptibility to ciprofloxacin (MIC, 0.125 to 1 microg/ml) in nontyphoid Salmonella isolates was common in Taiwan (48.1%) and Thailand (46.2%) and in S. enterica serotype Choleraesuis (68.8%) and S. Virchow (75.0%) from all countries. Reduced susceptibility to ceftriaxone (MIC, 2 to 8 microg/ml) remained uncommon in Asia, except in Taiwan (38.0%) or in S. Typhimurium (25.0%) from all countries.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Ceftriaxone / pharmacology*
  • Ciprofloxacin / pharmacology*
  • Drug Resistance, Multiple, Bacterial
  • Humans
  • Microbial Sensitivity Tests
  • Salmonella / classification
  • Salmonella / drug effects*
  • Serotyping

Substances

  • Anti-Bacterial Agents
  • Ciprofloxacin
  • Ceftriaxone