Abstract
The prion protein is infamous for its role in devastating neurological diseases, but its normal, physiological function has remained mysterious. A new study uses the experimentally tractable zebrafish model to obtain fresh clues to this puzzle.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cadherins / metabolism
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Calcium / metabolism
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Cell Adhesion*
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Cell Line
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Embryo, Nonmammalian / metabolism
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Embryo, Nonmammalian / physiology*
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Humans
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Morphogenesis
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Neurons
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PrPC Proteins / metabolism
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PrPC Proteins / physiology
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Prions / metabolism
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Prions / physiology*
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Zebrafish / embryology*
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Zebrafish / metabolism
Substances
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Cadherins
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PrPC Proteins
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Prions
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Calcium