Abstract
Tim Anderson discusses a new study of molecular variation in alleles at the dihydropteroate synthase locus, which underlies resistance to sulfadoxine, in over 5,000 parasites from 50 locations.
Publication types
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Comment
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Research Support, N.I.H., Extramural
MeSH terms
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Africa / epidemiology
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Alleles
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Animals
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Antimalarials / pharmacology*
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Dihydropteroate Synthase / genetics
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Drug Combinations
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Drug Resistance / genetics*
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Humans
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Malaria, Falciparum / drug therapy*
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Malaria, Falciparum / epidemiology
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Malaria, Falciparum / parasitology
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Malaria, Falciparum / prevention & control
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Maps as Topic
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Plasmodium falciparum / drug effects*
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Plasmodium falciparum / enzymology
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Plasmodium falciparum / genetics
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Plasmodium falciparum / isolation & purification
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Polymorphism, Single Nucleotide
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Population Surveillance
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Protozoan Proteins / genetics
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Pyrimethamine / pharmacology
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Selection, Genetic
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Sulfadoxine / pharmacology
Substances
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Antimalarials
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Drug Combinations
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Protozoan Proteins
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fanasil, pyrimethamine drug combination
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Sulfadoxine
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Dihydropteroate Synthase
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Pyrimethamine