Sequence of the gene encoding the major outer membrane protein of the mouse pneumonitis biovar of Chlamydia trachomatis

Gene. 1991 Sep 30;106(1):137-8. doi: 10.1016/0378-1119(91)90579-z.

Abstract

The gene encoding the major outer membrane protein of the Chlamydia trachomatis mouse pneumonitis biovar was sequenced and the amino acid sequence deduced. The primary structure of this protein is similar to that of the lymphogranuloma venereum and trachoma biovars in that it consists of four variable domains interspersed with five constant domains. This protein may be an ideal candidate for a vaccine in chlamydia-infected mouse experimental models.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Bacterial Outer Membrane Proteins / genetics*
  • Base Sequence
  • Chlamydia trachomatis / genetics*
  • Chlamydia trachomatis / metabolism
  • DNA, Bacterial
  • Genes, Bacterial
  • Lung Diseases / microbiology
  • Mice
  • Molecular Sequence Data
  • Porins*
  • Species Specificity

Substances

  • Bacterial Outer Membrane Proteins
  • DNA, Bacterial
  • Porins
  • omp1 protein, Chlamydia trachomatis

Associated data

  • GENBANK/M59725
  • GENBANK/M59726
  • GENBANK/M59727
  • GENBANK/M59728
  • GENBANK/M63990
  • GENBANK/M64171
  • GENBANK/S61507
  • GENBANK/S63856
  • GENBANK/S63863
  • GENBANK/S65055