A method to build an analytic model of the 10B(n,alpha)7Li reaction rate space distribution for boron neutron capture therapy (BNCT)

Appl Radiat Isot. 2009 Jul;67(7-8 Suppl):S149-52. doi: 10.1016/j.apradiso.2009.03.037. Epub 2009 Mar 27.

Abstract

This work provides the basis of a methodology to build a deterministic model for the spatial distribution of the (10)B(n,alpha)(7)Li reaction rate in boron neutron capture therapy (BNCT), as a function of space variables, boron concentration and beam incidence angle in homogeneous isotropic environments but also in different heterogeneous environments. Building the analytic function in a simple homogeneous environment with numerical methods leads to a mathematical formulation of the (10)B(n,alpha)(7)Li reactions rate.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Borates / therapeutic use*
  • Boron / therapeutic use
  • Boron Neutron Capture Therapy / statistics & numerical data*
  • Humans
  • Isotopes / therapeutic use
  • Lithium Compounds / therapeutic use*
  • Models, Statistical
  • Phantoms, Imaging / statistics & numerical data
  • Radiation-Sensitizing Agents / therapeutic use*
  • Radiotherapy Planning, Computer-Assisted / statistics & numerical data*

Substances

  • Borates
  • Isotopes
  • Lithium Compounds
  • Radiation-Sensitizing Agents
  • lithium borate
  • Boron