Abstract
A robust water-in-oil microemulsion method of making water-dispersible ultra-small (<30 nm) size fluorescent chitosan nanoparticles is reported for the first time and specific targeting of these FCNPs to human leukemia cells via aptamer recognition is demonstrated.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Cell Line, Tumor
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Chitosan / chemical synthesis*
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Chitosan / chemistry
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Flow Cytometry
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Fluorescent Dyes / chemical synthesis*
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Fluorescent Dyes / chemistry
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Humans
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Microscopy, Electron, Transmission
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Nanoparticles / chemistry*
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Nanoparticles / ultrastructure
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Water / chemistry*
Substances
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Fluorescent Dyes
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Water
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Chitosan