Management of central diabetes insipidus with oral desmopressin in a patient with ectrodactyly and cleft lip/palate (ECP) syndrome

Eda Ozaydin; Zehra Aycan; Arzu Meltem Yusufoğlu; Ergun Cetinkaya; Saime Ergen; Sevim Unal; Gülşen Köse

Management of central diabetes insipidus with oral desmopressin in a patient with ectrodactyly and cleft lip/palate (ECP) syndrome

Turk J Pediatr. 2009 Jan-Feb;51(1):89-93.

Authors

Eda Ozaydin¹, Zehra Aycan, Arzu Meltem Yusufoğlu, Ergun Cetinkaya, Saime Ergen, Sevim Unal, Gülşen Köse

Affiliation

¹ Ankara Dişkapi Children's Hospital, Ankara, Turkey.

PMID: 19378901

Abstract

We present a female infant with facial abnormalities such as bilateral cleft lip and palate, ectrodactyly and central diabetes insipidus. She had a history of recurrent hypernatremic attacks and she was treated successfully with oral desmopressin. As an alternative to the nasal route, long-term management was achieved using oral route and she had a favorable growth and development during infancy.

Publication types

Case Reports

MeSH terms

Abnormalities, Multiple*
Antidiuretic Agents / administration & dosage
Antidiuretic Agents / therapeutic use*
Cleft Lip / epidemiology*
Cleft Palate / epidemiology*
Deamino Arginine Vasopressin / administration & dosage
Deamino Arginine Vasopressin / therapeutic use*
Diabetes Insipidus, Neurogenic / drug therapy*
Diabetes Insipidus, Neurogenic / epidemiology
Diabetes Insipidus, Neurogenic / metabolism
Female
Fingers / abnormalities*
Humans
Infant, Newborn
Magnetic Resonance Imaging
Toes / abnormalities*

Substances

Antidiuretic Agents
Deamino Arginine Vasopressin