Abstract
Essential oil from flowers (FL) and vegetative parts (VP) of Achillea ligustica (Asteraceae), naturalized after cultivation in central Italy, was investigated by GC-FID and GC-MS. The most abundant components were linalool, viridiflorol, beta-pinene, 1,8-cineole and terpinen-4-ol. The antioxidant assays (DPPH and ABTS radical scavenging assays, and beta-carotene bleaching test) demonstrated a moderate activity of essential oils. The antimicrobial activity was evaluated by the broth micro-dilution method on 6 microbial strains and showed to be quite strong against the cariogenic Gram-positive Streptococcus mutans, suggesting that this essential oil could be a valid candidate for anti-cariogenic formulations. Moderate cytotoxic activity was observed in assays on four tumour cell lines by MTT assay.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Achillea / chemistry*
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Anti-Bacterial Agents / isolation & purification
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Anti-Bacterial Agents / pharmacology*
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Anti-Bacterial Agents / therapeutic use
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Antineoplastic Agents, Phytogenic / isolation & purification
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Antineoplastic Agents, Phytogenic / pharmacology*
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Antineoplastic Agents, Phytogenic / therapeutic use
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Antioxidants / isolation & purification
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Antioxidants / pharmacology*
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Antioxidants / therapeutic use
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Benzothiazoles
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Biphenyl Compounds
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Cell Line, Tumor
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Dental Caries / drug therapy
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Flowers
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Humans
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Italy
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Oils, Volatile / chemistry
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Oils, Volatile / pharmacology*
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Oils, Volatile / therapeutic use
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Phytotherapy*
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Picrates
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Plant Oils / chemistry
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Plant Oils / pharmacology*
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Plant Oils / therapeutic use
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Plant Structures
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Streptococcus mutans / drug effects
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Sulfonic Acids
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Thiazoles
Substances
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Anti-Bacterial Agents
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Antineoplastic Agents, Phytogenic
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Antioxidants
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Benzothiazoles
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Biphenyl Compounds
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Oils, Volatile
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Picrates
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Plant Oils
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Sulfonic Acids
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Thiazoles
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2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid
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1,1-diphenyl-2-picrylhydrazyl