Is immunohistochemistry less sensitive than quantitative reverse transcriptase polymerase chain reaction for hormone receptor status determination in breast cancer?

J Clin Oncol. 2009 Jun 1;27(16):2733; author reply 2734-5. doi: 10.1200/JCO.2009.22.0269. Epub 2009 Apr 20.
No abstract available

Publication types

  • Comment
  • Letter

MeSH terms

  • Biomarkers, Tumor / analysis*
  • Biomarkers, Tumor / genetics
  • Breast Neoplasms / chemistry*
  • Breast Neoplasms / genetics
  • Breast Neoplasms / pathology
  • Cost Savings
  • Cost-Benefit Analysis
  • Female
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Immunohistochemistry* / economics
  • Neoplasm Staging
  • Predictive Value of Tests
  • Prognosis
  • RNA, Messenger / analysis
  • Receptors, Estrogen / analysis*
  • Receptors, Estrogen / genetics
  • Receptors, Progesterone / analysis*
  • Receptors, Progesterone / genetics
  • Reproducibility of Results
  • Reverse Transcriptase Polymerase Chain Reaction* / economics

Substances

  • Biomarkers, Tumor
  • RNA, Messenger
  • Receptors, Estrogen
  • Receptors, Progesterone