[A case of locally advanced rectal cancer responding to FOLFOX]

Gan To Kagaku Ryoho. 2009 Apr;36(4):659-61.
[Article in Japanese]

Abstract

The 57-year-old man was underwent sigmoid colostomy due to unresectable rectal carcinoma. Then he was treated with chemotherapy of levofolinate/5-fluorouracil/oxaliplatin(FOLFOX). After completion of 12 courses of chemotherapy, MR revealed responses. The patient underwent a low anterior resection. Preoperative chemotherapy with FOLFOX appears a promising regimen for patients with unresectable rectal cancer.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Fluorouracil / therapeutic use
  • Humans
  • Leucovorin / therapeutic use
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neoplasm Invasiveness / pathology
  • Neoplasm Staging
  • Organoplatinum Compounds / therapeutic use
  • Proctoscopy
  • Rectal Neoplasms / drug therapy*
  • Rectal Neoplasms / pathology*
  • Rectal Neoplasms / surgery

Substances

  • Organoplatinum Compounds
  • Leucovorin
  • Fluorouracil

Supplementary concepts

  • Folfox protocol