Abstract
Small- and medium-vessel vasculitis is a common manifestation in systemic lupus erythematosus (SLE) and may occur in any organ. However, acute acalculous cholecystitis is a rare abdominal manifestation in SLE, especially in children. We report a case of a 12-year-old patient who initially presented with AAC and seizure. Follow-up investigation diagnosed SLE, and brain magnetic resonance imaging had hyperintense white matter lesions in cortico-subcortical regions. The patient was successfully treated with pulse methylprednisolone and cyclophosphamide without surgical intervention.
MeSH terms
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Acalculous Cholecystitis / diagnosis
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Acalculous Cholecystitis / drug therapy
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Acalculous Cholecystitis / etiology*
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Acute Disease
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Child
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Cyclophosphamide / administration & dosage
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Diagnosis, Differential
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Dose-Response Relationship, Drug
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Drug Therapy, Combination
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Female
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Follow-Up Studies
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Glucocorticoids / administration & dosage
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Humans
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Immunosuppressive Agents / administration & dosage
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Lupus Erythematosus, Systemic / complications*
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Lupus Erythematosus, Systemic / diagnosis
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Lupus Erythematosus, Systemic / drug therapy
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Magnetic Resonance Imaging
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Methylprednisolone / administration & dosage
Substances
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Glucocorticoids
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Immunosuppressive Agents
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Cyclophosphamide
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Methylprednisolone