Comparison of preservation methods for enterotoxigenic Escherichia coli producing heat-labile enterotoxin

J Clin Microbiol. 1991 Oct;29(10):2326-8. doi: 10.1128/jcm.29.10.2326-2328.1991.

Abstract

Ten strains of enterotoxigenic Escherichia coli producing heat-labile enterotoxin (LT) were preserved under 12 different conditions. After 1 month, 9 months, and 3 years of preservation, the cultures were recovered and examined for LT production. Preservation of the cultures on Dorset Egg Medium at 4 degrees C and preservation by freezing the cell suspensions in tryptic soy broth with 20% glycerol were found to be suitable preservation methods; all strains were alive for 3 years and had a minimum loss of LT production.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Toxins / biosynthesis*
  • Bacterial Toxins / genetics
  • Bacteriological Techniques
  • Cryopreservation
  • Culture Media
  • Enterotoxins / biosynthesis*
  • Enterotoxins / genetics
  • Escherichia coli / genetics
  • Escherichia coli / isolation & purification
  • Escherichia coli / metabolism*
  • Escherichia coli Proteins*
  • Evaluation Studies as Topic
  • Humans
  • Plasmids
  • Preservation, Biological / methods*

Substances

  • Bacterial Toxins
  • Culture Media
  • Enterotoxins
  • Escherichia coli Proteins
  • heat-labile enterotoxin, E coli